Luna

Luna, commonly known as the Moon, was the only natural satellite of Earth. It was home to the New Horizons Lunar Colony, a long-established human city. In its final years Luna sheltered Isaac Clarke in hiding, concealed a shrouded Red Marker test laboratory run by EarthGov, and suffered a Necromorph outbreak when the Circle tore that shroud away. (Dead Space 3)

Colonization#

The games say little about how Luna was first settled. Background material outside the games fills in an early history for New Horizons, but none of it appears in the games themselves, and the colony Dead Space 3 shows is simply an old, crowded city that has grown up around its mining sites and transit lines. (Dead Space 3)

What the game does show is a place built in layers. Isaac's apartment block, the concourse below it and the route to Washington Station are cramped and run-down, the look of a city that has been added to for a long time. (Dead Space 3)

The colony in decline#

By the time Isaac moved there, New Horizons was no longer a place people went to get rich. It was where he could disappear, a run-down city where an engineer with a famous name could keep his head down. (Dead Space 3)

EarthGov still kept a presence on the Moon, and still judged it significant enough to hide a Red Marker test site within the city. (Dead Space 3)

A refuge for Isaac Clarke#

After escaping the Sprawl, Isaac Clarke and Ellie Langford went into hiding on Luna from EarthGov and the Unitologists. The two became romantically involved and took up residence in the Red Moon Apartments of the New Horizons Colony. Ellie had replaced the eye she lost on Titan Station with an artificial one. Isaac, despite having freed himself from the Marker's mental grip on Titan Station, still suffered its lingering effects, and his mind still held the secrets the artifacts had planted there. (Dead Space 3; Dead Space 2)

The couple eventually separated over Isaac's refusal to keep fighting the Markers. Ellie left to pursue a solution to the Marker crisis while Isaac remained on the colony, forced underground to avoid capture. He stayed there until Captain Robert Norton and Sergeant John Carver of EarthGov apprehended him at his apartment. Isaac at first refused to help them, partly because they were EarthGov soldiers, but agreed once he was told that Ellie had gone toward Tau Volantis and was missing. (Dead Space 3)

The Luna Marker#

The Red Marker hidden in the heart of New Horizons appeared to be nearly as large as the Site 12 Marker that had destroyed Titan Station. EarthGov encased it in a shroud that prevented the Marker's signal from spreading into the surrounding city, and according to Jacob Danik, the shroud had a laboratory built within it, possibly similar to the facility hidden in Titan Station's Government Sector. A similar structural design was later used at the EarthGov facility called Marker Shroud 4 on Uxor, where the enclosure seemingly controlled the Marker's exposure and kept its signal from reaching the surrounding area. So long as the shroud stood, the people of the colony remained unaware of what EarthGov kept among them. (Dead Space 3; Dead Space 2; Dead Space: Liberation)

The Circle's assault#

The Circle, a militarized extremist faction of the Church of Unitology led by Jacob Arthur Danik, attacked Luna's colony. Danik and his men had followed Norton's group to New Horizons and discovered that Norton was after Isaac Clarke, whom the Circle's inner leadership regarded as a heretic for killing the Aegis VII and Titan Station Markers. As his forces prepared the assault, Danik spread an automated speech from an airship over the top of the colony, preaching that the end of mankind had come and that the time of humanity's glorious rebirth was imminent. (Dead Space 3)

The Circle cut down the colony's EarthGov security forces and captured Isaac. Danik forced him to watch as the shroud and the laboratory around the Red Marker were detonated, exposing the artifact in its endeavor to "free" it from EarthGov's containment. Danik then attempted to execute Isaac, who evaded the shot and fell down a shaft into a pile of dead EarthGov security officers. While Isaac lay unconscious, the Marker's signal leaked across the city and a Necromorph infestation began ravaging the colony, turning the dead into creatures. Among the forms that stalked New Horizons were Fodders, Necromorphs that used a human-like facade to hide their transformed bodies. Isaac fought his way through the colony's transformed inhabitants and the Circle's soldiers to escape aboard the USM Eudora, bound for Tau Volantis. Behind him, the outbreak presumably wiped out the New Horizons colony. (Dead Space 3)

Silence over Luna#

After the events on Tau Volantis, Isaac Clarke and John Carver returned to Earth and Luna aboard the CMS Terra Nova, the Sovereign Colonies vessel recovered from above Tau Volantis. They attempted to raise anyone on the radio channels of Earth and Luna, but all they received was the haunting sound of people being slaughtered by Necromorphs. The Brethren Moons had arrived at Earth and were in the process of consuming the human race. One of the Brethren Moons then appeared directly in front of the Terra Nova, seemingly crashing into the ship. No further word ever came from Luna or the colony that had been humanity's first foothold beyond its homeworld. (Dead Space 3: Awakened)